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BIO- AND SOFT MATERIALS

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New strategies for smart biointerfaces

This symposium will bring together the diverse community of materials scientists, chemists, biologists and bioengineers focused on synthesis, characterization and design of smart biointerfaces. The most recent advances in fundamental studies, nano-bio material synthesis and biodevice design will be presented, offering unique opportunities for dissemination and synergy development.

Scope:

Interfacial interactions between solid surfaces and biomolecules and cells underpin function and performance of materials in wide ranging applications, from implantable biodevices, to sensors, bioreactors and theranostic agents. Frontier research in this field focuses on achieving a deeper understanding of fundamental solid-bio interactions, while also on developing novel strategies for eliciting desirable bioresponses. Therefore, research in biointerfaces is cross-cutting and integrates multifaceted expertise in materials synthesis and modification, heterogeneous reactivity and charge transfer, nanoengineering, biochemistry, cell adhesion and biofilm regulation among others.

This symposium will bring together this diverse community of researchers to share progress on novel methodologies for the creation of smart biointerfaces with specific functionality and to disseminate the latest advances on our understanding of the solid-bio interface. Advanced methods for nanomaterial synthesis and modification have enabled new tools for regulating biomolecule conformation and cell adhesion at surfaces with nanoscale resolution through the control of topography, chemistry and morphology. Recent progress in selective surface modification of nanostructures, such as hot-spot functionalization, as well as the integration of tools from synthetic biology and electrochemistry have further contributed to our toolkit for the creation of tailor-made biointerfaces. Such progress in turn opens the door to the development of novel model systems for probing interactions of biomolecules, cells and tissues with solid materials, which are amenable to modelling via computational approaches, thus bridging the gap between theory and experiment. This symposium will explore synergies among these focal areas of research bringing together the latest advances in synthetic, device and modelling aspects of biointerfaces with the aim of catalysing the advent of the next generation of smart biomaterials.

Hot topics to be covered by the symposium:

The symposium will focus on the following themes in the area of biointerfaces:

  1. Nanostructured biointerfaces: including nano-bio, nanomedicine, nanoinstrumental characterization, nanoplasmonics
  2. Surface-cell interfaces and biofilms: including biofilm regulation, cell-electrode interfaces, bioelectrocatalysis, cell adhesion and proliferation at surfaces, smart antibacterial surfaces.
  3. Adaptive and responsive biomaterials: including smart polymers, stimuli responsive materials, controlled release, biosensing.
  4. Bioinspired materials: including functional biopolymer surfaces, supported biomimetic membranes, nano-biomolecule interface.
  5. Novel fabrication strategies for smart biointerfaces: including wetting modulation, bioconjugation, biosensing, bioactive functionality, array surface design.

List of invited speakers:

  • Matthew R. Lockett (Department of Chemistry, University of North Carolina at Chapel Hill, USA; confirmed): Healthy tissue to tumor models: using cellulose-based materials as scaffolds for 3D cell cultures
  • Nicolas Brun (Institut Charles Gerhardt Montpellier, France; confirmed): Enzymes at carbon electrodes: when porosity matters
  • Seiya Tsujimura (Division of Materials Science, Faculty of Pure and Applied Sciences; Univ. of Tsukuba, Japan; confirmed): Enzyme-based bioelectrocatalysis and its application to enzymatic biofuel.
  • Klaus Jandt (Institute of Materials Science and Technology (IMT); Friedrich Schiller University Jena, Germany, confirmed): Towards multifunctional and smart biointerfaces.
  • Lia Addadi (Department of Structural Biology; Weitzmann Inst. Israel, confirmed): Pending title.
  • Paolo Netti (Center for Advanced Biomaterials for Health Care; IIT - Istituto Italiano di Technologia, Italy, confirmed): Pending title.
  • Henk Busscher (Faculty of Medicine; University of Groningen, Netherlands, confirmed): Pending title

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Symposium organizers
Frédéric BARRIEREUniversité de Rennes 1

Institut des Sciences Chimiques de Rennes, Campus de Beaulieu, 35042 Rennes, France

+33 2 23 23 59 43
frederic.barriere@univ-rennes1.fr
Giovanni MARLETTAUniversity of Catania

Laboratory for Molecular Surfaces and Nanotechnology V.le A.Doria 6 Catania Italy

+39 95 7385130
gmarletta@unict.it
Mathieu ETIENNEUniversité de Lorraine

Laboratoire de Chimie Physique et Microbiologie pour les Matériaux et l'Environnement, CNRS - LCPME, 405, rue de Vandoeuvre, F-54600 Villers-lès-Nancy, France

+33 3 72 74 73 82
mathieu.etienne@univ-lorraine.fr
Paula COLAVITATrinity College Dublin

School of Chemistry, CRANN and AMBER Research Centres - School of Chemistry, College Green, Dublin 2, Ireland

+353 1 8963562
colavitp@tcd.ie