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Biomaterials and soft materials

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Biohybrid nanomaterials: bioinspired, DNA- and peptide-based assemblies for sensing, delivery and electronics

The combination of biomolecules and synthetic constructs can lead to biohybrid nanostructures with new functions that emerge through design at the molecular and supramolecular levels. This symposium will encompass the design, characterization, and the recent applications of bioinspired and biohybrid assemblies in sensing, delivery, and bioelectronics.

Scope:

The scope of this symposium is to explore the many facets of biohybrid nanomaterials, dealing with their design, synthesis, characterization, self-assembly, modeling, properties, functions and biological investigations (in vitro, in vivo). The symposium will cover bio-supramolecular and bio-inspired assemblies, peptide-based and DNA-templated nanostructures, as well as biomolecular nanoarrays, with perspectives and applications in (bio)sensing, delivery, and bioelectronics.

Bioinspiration and biomimicry are nowadays seen as sound approaches to evolve towards sustainable and smart materials for applications in the fields of healthcare and information technology. In this context, biomolecules such as peptides or nucleic acids can be seen as natural, information-rich, and tunable scaffolds. Thus, researchers are seeking novel functions by interfacing biomolecules with synthetic nanomaterials (small organic compounds, macromolecules, nanoparticles, carbon nanotubes and 2D nanomaterials) in a unique fashion that lead to the self-construction of functional static and dynamic biohybrid nanostructures of high interest for sensing, delivery and bioelectronic applications. Mastering this self-assembly process requires proper molecular design of the biomolecular and synthetic partners, and a synergistic set of interactions at the supramolecular level.

The study of biohybrid nanomaterials requires a multidisciplinary approach, hence this symposium aims at bringing together materials scientists, supramolecular chemists, biophysicists, and computational chemists to share the various viewpoints and approaches in the emerging field of biohybrid nanomaterials. Particular emphasis will be given to DNA- and peptide-based strategies, but more general approaches employing supramolecular interactions to control the formation of biohybrid nanostructures are within the scope of the symposium.

Hot topics to be covered by the symposium:

  • Bio-supramolecular nanostructures
  • DNA-templated nanostructures
  • Peptide- and polypeptide-based self-assembled nanostructures
  • Interfacing biomolecules with nanoparticles/nanotubes/nanosheets
  • Stimuli-responsive biomolecular assemblies
  • Molecular modeling of hybrid biomolecular structures
  • Optical/Electrical/Electrochemical sensing based on biomolecular hybrids
  • Single-molecule bioelectronics
  • Supramolecular approaches for delivery applications

List of invited speakers (confirmed):

  • Rein Ulijn, Nanoscience Initiative at the Advanced Science Research Center, City University of New York
    “Design Principles for Peptide Matter with Life-Like Functions”
  • Jennifer N. Cha, University Colorado Boulder
    “Generating Renewable Fuels from Bio-Nano Architectures”
  • Sébastien Lecommandoux, ENSCBP, CNRS, University of Bordeaux
    “Bioactive nanomaterials by design from self-assembly of polypeptide-based biohybrid copolymers”
  • Ignacio Alfonso, Institute for Advanced Chemistry of Catalonia (IQAC-CQSIC), Barcelona
    “Molecular recognition and dynamic covalent chemistry applied to chemical biology”
  • Davide Bonifazi, School of Chemistry, Cardiff University
    “Tailoring functional architectures with peptide templates”
  • Mathieu Linares, Linköping University
    “Theoretical investigations of DNA-molecule interactions”
  • Peter Crowley, NUI Galway
    “Programmable Protein Assembly by Supramolecular Receptors”
  • Mihail Barboiu, CNRS, University of Montpellier
    “Dynamic Constitutional Frameworks – new tools for biorecognition”
  • Javier Montenegro, Center for Research in Biological Chemistry and Molecular Materials, University of Santiago de Compostel
    “Supramolecular Lessons for New Biomaterials in Gene Delivery and Cytoskeleton Mimics”

List of scientific committee members:

  • Beatriu Escuder, University of Castellon
  • Subi J. George, JNCASR, Bangalore, India
  • Andrés de la Escosura, Universidad Autónoma de Madrid
  • Sébastien Clément, University of Montpellier
  • Christian Nielsen, Queen Mary University of London
  • Stefan Matile, University of Geneva
  • John Hardy, Lancaster University
  • Tanja Weil, Max Planck Institute for Polymer Research, Mainz (to be confirmed)
  • Luc Brunsveld, Technische Universiteit Eindhoven

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Symposium organizers
Elisabeth GARANGERUniversité de Bordeaux

Laboratoire de Chimie des Polymères Organiques (LCPO), 16 avenue Pey-Berland, 33607 Pessac, France

+33 540006693
elisabeth.garanger@enscbp.fr
Mathieu SURIN (Main)University of Mons – UMONS

Laboratory for Chemistry of Novel Materials, 20 Place du Parc - 7000 Mons, Belgium

+32 65 373855
mathieu.surin@umons.ac.be
Matteo PALMAQueen Mary University of London

Room 1.11, Joseph Priestley Building, Mile End Road, London E1 4NS, U.K.

+44 20 7882 6601
m.palma@qmul.ac.uk
Sébastien ULRICHIBMM, Université de Montpellier, CNRS

ENSCM, 8 rue de l’école normale, 34090 Montpellier, France

+33 467144346
sebastien.ulrich@enscm.fr